Blood and neoplastic diseases. Haemostasis, haemorrhage, and thrombosis.
نویسندگان
چکیده
منابع مشابه
Haemostasis, Haemorrhage, and Thrombosis
The pathophysiology of the haemostatic mechanism is central to both haemorrhagic disease and thrombosis, and rational therapy of such diseases must be based on understanding it. Blood loss after injury is minimized by a complex series of interrelated reactions involving vascular constriction, the production of a platelet plug, and the formation of fibrin through the coagulation mechanism. Proba...
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Evidence and information sources. The contribution of leukocytes and red cells to thrombogenesis has been reviewed. Moreover, the prevalence of thrombosis as a complication of hematologic diseases has been examined. The authors are involved in the investigation and management of acute and chronic hematologic diseases as well as in investigation of thrombophilia. Pub-Med was employed as a source...
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The metabolic syndrome (metS), a concurrence of abdominal fat, disturbed glucose and insulin metabolism, dyslipidemia, and hypertension has been strongly associated not only with subsequent development of type 2 diabetes but also with atherothrombosis. The physiopathology of this association is complex. The metS affects the thrombogenicity of circulating blood. Apart from its effect on platelet...
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Gene targeting in the mouse genome has generated a variety of mouse lines with complete deficiencies in virtually all know factors involved in haemostasis. In addition, transgenic techniques have produced mice with altered expression of some of these factors, which are required in cases of embryonic lethality (1, 2). Based on these studies, in general, mouse haemostasis is very similar to haemo...
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ژورنال
عنوان ژورنال: BMJ
سال: 1974
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.3.5934.787